Objective: This study seeks to determine the contributory factors to successful succession and 125 post-succession performance.And the role of these factors in the post-succession financial and non-financial performance of family-owned SMEs in South Eastern Nigeria.Research Design & Methods: The adopted quantitative methodology is interview.In each
Zinc finger protein 521 (ZNF521) participates in the self-renewal of hematopoietic stem cells, and its abnormal expression has been implicated to promote leukemia.However, the specific role of ZNF521 in leukemia has not been fully understood.In this study, we aimed to further elucidate its role.Using acute leukemia cell line THP-1, we demonstrated
The effects of genetic variation on gene regulation in the developing mammalian embryo remain largely unexplored.To globally quantify these effects, we crossed two divergent mouse strains and asked how genotype of the mother or of the embryo drives gene expression phenotype genomewide.Embryonic expression of 331 genes depends on the 125 genotype of
Lung squamous cell carcinomas (SCCs) are highly aggressive tumors, and there is currently no effective targeted therapy owing to the lack of specific mutation targets.Compared with lung adenocarcinoma (ADCs), lung SCCs reportedly utilized higher levels of glucose metabolism to meet the anabolic and catabolic needs required to sustain rapid tumor Co